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pymysql.err.InterfaceError after some hours of usage

?? ???????, 2 ????????? 2019 - 8:26:38 ?.?. UTC+3, ? ??????? Inada Naoki ??????:
> MySQL connection can be closed automatically by various reasons.
> For example, `wait_timeout` is the most common but not only reason for
> closing the connection.
> You should connect and close MySQL connection for each HTTP request.
> Or you can use more smart connection pool (e.g. Engine in SQLAlchemy).
> It provides `pool_recycle` and `pool_pre_ping` options.
> https://docs.sqlalchemy.org/en/13/core/pooling.html#setting-pool-recycle

You mean that every time i insrt/update and in general having a cur.execute() i then need to close the pymysql connection in order to not have this error?