Ready to take the plunge

I have a new dedicated server. I'm planning on migrating from my existing
server to the new one, and making some changes along the way.

I'd like to set up dbmail, with PostgreSQL, Postfix, and some antivirus and
spam filtering.

I've been following things for a while, lurking in the background, but
haven't seen a lot of clear information.

What's the best version to use for the primary mail server of a small to
medium sized organization? Or, is dbmail still not ready for prime time on a
production server? 

Is there a vacation program yet? I know there was talk a while back about
not having a vacation program available. And a couple of other features too.

Any advice, tips, tricks, and hints on what to do (or what NOT to do) are
greatly appreciated.

Thanks,
Greg