hardstatus line / startup foo

Is there a way to make different color'd status lines and/or source
different .bashrc files when I create a new screen?

Like screen 0 has a white status line, screen 1 is blue and screen0 
sources .bashrc0, etc...

Or should I just create a mega startup script that does all this?  If 
this is possible, do you guys have an example of how do this?

Tony