CryoNet #22664 - #22667

CryoNet - Sat 11 Oct 2003

    #22664: Excerpts from July 2003 issue of Periastron now on ACS website 
[Edgar Swank]
    #22665: Reversal of cellular senescence [Henry R. Hirsch]
    #22666: 109'th update on fly longevity experiments [Doug Skrecky]
    #22667: first tv interview [Christine Gaspar]

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Message #22664
Date: Fri, 10 Oct 2003 08:28:59 -0700
From: Edgar Swank <cryoprez@xxxxxxx>
Subject: Excerpts from July 2003 issue of Periastron now on ACS website

ACS has just published excerpts from the latest issue of
Periastron, by noted writer Thomas Donaldson, on our website.
Below is a complete index for this issue. Starred articles are
published in full on the website.


1 July, 2003 -- Volume 7, Number 4

  Never All of Us Together                       *
  Both Nano and Quantum Computing
        Advance                                  *
  What Is It?
  Now, Life at 130 C                             *

  Science Reports
      New Insights into Our Brain Anatomy
      More Work against Brain Ischemia
      More on Growth of New Neurons
      New Dendrites and Axons, Too

  A Precis for Rushed Readers                    *


Edgar W. Swank   <cryoprez@xxxxxxx>
President - American Cryonics Society
http://AmericanCryonics.org

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Message #22665
Date: Fri, 10 Oct 2003 17:00:44 -0400
From: "Henry R. Hirsch" <hrhirsch@xxxxxxx>
Subject: Reversal of cellular senescence

                                        October 10, 2003

        At an aging symposium held at the University of Kentucky yesterday, Dr. 
Judith Campisi, Senior Scientist at the Lawrence Berkeley National 
Laboratory, reported that cellular senescence can be reversed in normal 
human diploid cells in culture with the use of the protein p16. Cellular 
senescence is the cessation of cell division and ordinarily occurs at the 
"Hayflick limit" of approximately 50 population doublings. Previously, 
release from senescence, i.e. resumption of culture growth, had been 
possible only under regimens in which the cells displayed chromosome 
abnormalities.

        The results obtained in Dr. Campisi's laboratory constitute great 
progress 
toward the goal of reversing senescence. I asked her whether, within the 
next 50 years, it would be possible, based on her techniques, to reverse 
aging in a large multicellular organism. She said that was not likely but 
that reversal might be doable in an organ system, such as the 
cardiovascular system. We agreed that, ten years ago, we would have 
considered this impossible.

        In evaluating Dr. Campisi's positive remark, we should bear in mind (1) 
that she is talking about an extrapolation of today's biochemistry, not 
yet-to-be invented nanotechnology, and (2) that she is a world-renowned 
expert in cellular senescence. Cryonics would be of limited value if aging 
reversal were not part of the package, so hang in there folks. We have good 
reason to hope.

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Message #22666
Date: Fri, 10 Oct 2003 21:21:55 -0700 (PDT)
From: Doug Skrecky <oberon@xxxxxxxxx>
Subject: 109'th update on fly longevity experiments

    This is the 109'th update of my fly longevity experiments. Average
temperature was 25.5 C during this run. Estimated maximal longevity using
the formula (363 - T*11.2) is 77 days.
    Here I continue testing raw produce extracts. Dill was the most toxic
this time. Eggplant may have offered a small benefit early in the
experiment.

Run #109                 Percent Survival on Day
supplement        4   9  15 21 26 32 37 42 47 52 57 63
______________________________________________________
control one     100  93  89 70 52 22  7  4  0  -  -  -
control two     100  94  83 51 29 20 11  6  3  3  3  0
asparagus 8%     95  82  68 55 45 27  9  5  5  0  -  -
asparagus 33%   100  89  58 26 21  5  0  -  -  -  -  -
anise 8%         95  81  71 19 14  5  5  5  0  -  -  -
anise 33%       100  71  62 29 29 24  0  -  -  -  -  -
dill 8%         100  93  79 50 36  0  -  -  -  -  -  -
dill 33%          6   0   -  -  -  -  -  -  -  -  -  -
eggplant 8%     100 100 100 75 30 20  5  0  -  -  -  -
eggplant 33%    100 100  87 73 67 27  7  0  -  -  -  -
green beans 8%   95  75  70 20 15  5  5  5  0  -  -  -
green beans 33% 100  85  69 31 15  0  -  -  -  -  -  -
snow peas 8%    100  85  46 23 15 15  8  0  -  -  -  -
snow peas 33%   100  80  53 40 20 13 13  7  0  -  -  -

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Message #22667
Date: Fri, 10 Oct 2003 23:25:43 -0700 (PDT)
From: Christine Gaspar <christinegaspar1@xxxxxxxxx>
Subject: first tv interview

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Hi everyone. This afternoon, Brent Erskine and I did an interview for a 
television production called TKO (technical knockout). Its produced by Pyramid 
Productions, and I think is channelled throught Global / Canwest. It airs 
primarily in Western Canada, but those of you with time shifting from Rogers 
Cable might be able to pick it up. They will nevertheless send us a copy of the 
show on tape. I think it went incredibly well. We spoke with the videographer 
for more than an hour, and it was unscripted, which was nice. (I didn't read 
from the notes I had prepared, and Brent spoke off the cuff too) I'd like to 
thank Brent for participating. I think this will be a positive presentation of 
cryonics to the community at large. As well, being the first time either of us 
have done this, it was a great learning experience.
 
I hope that we can do more of these, on a regular basis, as I think it will go 
a long way towards one of our goals (at least one of mine anyways) of 
normalizing and legitimizing cryonics to the larger Canadian community.
 
Christine Gaspar
President, Cryonics Society of Canada

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